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FAQ ON IONIZED WATER
Learn About pH, ORP
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    What is alkaline ionized water?

    EVER SEEN A GLACIAL STREAM OR AN ICEBERG?

    It’s blue with minerals. It tastes totally different. It seems to enter the body lightly. It presents no resistance. You don’t ‘bloat’ like you may do with tap water or even filtered water.

    And the minerals are there not just to offer you those elements your system lacks, but also to ‘hold’ the real secret of glacial water; its antioxidant power. It’s filled with strong, pure hydroxyl ions, negatively charged hydrogen atoms that actively seek out positively charged oxygen free radicals which are already wrecking havoc on our bodies at a cellular level.

    This is naturally occurring ionized water, and just for once, technology has delivered a ‘clean’ answer to us, which emulates the same conversion of glacial H2O into pure alkaline, ionized, oxygenated drinking water, by ‘splitting’ H2O (two hydrogen atoms, one oxygen atom) into two separate streams of water;

    1. OH – One atom of oxygen and one atom of hydrogen negatively charged – the hydroxyl ion. This is the prized alkaline water that we drink and love.
    2. HO –One atom of hydrogen and one of oxygen. This is the acid water we use externally and for germicidal cleaning. For more details on the amazing properties of acid water,

    This ‘splitting’ of the H2O molecule happens in a sealed ionization chamber within your filter for ionized water, under exact control of a dedicated microcomputer, to ensure the exact same result time after time. As filtered tap water passes across  thirteen specially designed titanium electrodes, it separates into the two components above. We drink the alkaline ionized water and we apply the acid water. How simple and how wonderful! And in our own case, how healing!
    SO WHAT’S ALL THIS ABOUT “pH”?

    Fact: Almost all of us are slowly dying of excess acid.

    Fact: This need not be. Help is at hand.

    The pH scale ranges from 0 on the acidic side to 14 on the alkaline, and a solution is neutral if its pH is 7.  At pH 7, water contains equal concentrations of H+ and OH- ions. Substances with a pH less than 7 are acidic because they contain a higher concentration of H+ ions. The pH scale is a logarithmic scale, so a change of one pH unit implies a tenfold shift in the concentration of hydrogen ions.  pH 6 means you are ten times more acidic than pH 7.  pH 5 means you are a hundred times more acidic than pH 7.

    THE IMPORTANCE OF BALANCING pH

    Living things, including humans, are extremely sensitive to pH and function best (with certain exceptions, such as different portions of the digestive tract) when solutions are nearly neutral.  Most interior living matter (excluding the cell nucleus) has a pH of about 6.8. Blood plasma and other fluids that surround the cells in the body have a pH of 7.2 to 7.45.

    A blood pH of 6.9 can induce coma and death. That is why all bodily systems are secondary in importance to the system of pH balancing. Your body will willingly shut down digestion, alter temperature, rob your bones of calcium, and deprive your pancreas, just to maintain adequate fluid buffers of alkalinity to balance the ‘acid tide’ we inflict upon ourselves daily through diet and stress.

    However, your body possesses numerous special mechanisms to aid in stabilizing these fluids so that cells will not be subject to appreciable fluctuations in pH. Substances which serve as mechanisms to stabilize pH are called BUFFERS. Buffers have the capacity to bond ions and remove them from solution whenever their concentration begins to rise. Conversely, buffers can release ions whenever their concentration begins to fall, thus helping to minimize fluctuations in pH. This is an important function because many biochemical reactions normally occurring in living organisms either release or use up ions.

    Imagine now what a load is taken off your body if its primary safety system of pH balancing can be ‘stood down’ from a continual ‘full alert’ because you now have a plentiful supply of alkaline water!

    TAP WATER – WHAT IT IS AND ISN’T

    On the pH scale of 0 to 14, normal tap water measures out an approximately neutral 7, or slightly either side; acid in the case of rainwater, alkaline in the case of chemically altered municipal supplies. This water can be measured with an ORP (oxidation-reduction potential) meter, and its redox is +400 to +500 mV. Because it has a positive redox potential, it is apt to acquire electrons and oxidize other molecules, and then rob your body of electrons in the form of energy.

    Reduced Ionized Water, on the other hand, has a negative redox potential of approximately -250 to -250 mV. This means it has a large mass of electrons ready to donate to electron-thieving active oxygen in the form of free radicals. It is ‘live water’, similar in atomic structure to the waters that the Hunzakuts drank directly from glacial streams in the high Himalayas. (Note: Some salespeople will attempt to convince you that ORP measurement is not important. It is, and it can be easily measured.)
    How Your Water Ionizer Unit Works

    The water ionizer unit, about the size of a bread maker, is an electronic water filter connected to your kitchen water supply to perform controlled low voltage electrolysis on tap water before you drink it or use it in the kitchen for cooking or cleaning.

    A special attachment redirects tap water out of the faucet through a plastic hose into the water ionizer unit. Inside the unit, the water is first filtered through activated charcoal, removing common pollutants found in city water. Then this filtered water passes into a chamber equipped with platinum-coated titanium electrodes. Here is where the electrolysis takes place.

    Cations (positive ions) gather at the negative electrodes creating cathodic or reduced water. Anions (negatively charged ions) gather at the positive electrode to make anodic or oxidized water. By this electrolysis process the reduced water not only gains an excess amount of electrons (e-), but the H2O clusters are reduced in size from about ten to 13 molecules per cluster to five to six molecules per cluster.

    The reduced ionized water comes out of the faucet, and the oxidized water comes out of a separate hose leading into the sink. You can use the reduced water for drinking or cooking. The oxidation potential of the oxidized water makes it a good sterilizing agent, ideal for washing your hands, cleaning food or kitchen utensils, and treating minor wounds and skin problems.

    Ionized Water and Hydrogen Water - Fight or Prevent over 170


    Here is a partial list of diseases molecular hydrogen helps.

    • Alexander disease
    • Allergies
    • Alzheimer's disease and other dementias
    • Angina
    • Asthma
    • Atherosclerosis
    • Athlete's foot
    • Atopic dermetitis
    • Autoimune disorders
    • Bed sores
    • Bone Loss
    • Cancer (various types)
    • Cardio renal symptoms
    • Cataracts
    • Cerebral hemorrhage
    • Chemo's negative side effects
    • Chrones disease
    • Chronic fatigue syndrome
    • Cirrhosis
    • Collagen disease
    • Colon diseases
    • Cystic fibrosis
    • Dehydration
    • Diabetes mellitus
    • Diabetic necrosis
    • Frontotemporal lobar degeneration
    • Glaucoma
    • Gout
    • Heart attacks
    • Heart disease or coronary artery disease,
    • HGC disorders
    • High blood pressure
    • Huntington's disease
    • Hypersensitive disorders

    Hypertension

    • Inflammatory disorders
    • Ischemic brain injuries
    • Kawasaki's disease
    • Kidney disease
    • Liver disease
    • Lupus
    • Malaise
    • Metabolic syndrome
    • Muscle fatigue of athletes

    Benefits Demonstrated in Research Studies & Clinical Trials

    Here are over 100 scientific articles showing that ionized water and hydrogen water benefits virtually every body-part and disease.

    Note: Micro-biologists call ionized water electrically reduced water, electrochemically reduced water, electrolyzed reduced water, reduced water or ERW.



    Benefits Demonstrated in Research Studies & Clinical Trials

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    Spanning over 20 years worth of treating patients with ionized water Blood Pressure  

    Use of Ionized water in hypochlorhydria or achlorhydria Prof. Kuninaka Hironage, Head of Kuninaka Hospital

    "The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels ."

    2017

    Myocardial Infarction

    The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans. [Human study shows inhaling hydrogen is safe and improves the markers of hypertension.]

    2019

    Hypertension

    Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. [Animal study shows hydrogen reduces hypertension and left ventricular hypertrophy.]

    2018

    Chronic Heart Failure

    Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. [Animal study shows hydrogen reduces the symptoms of chronic heart failure.]

    2016

    Cardiopulmonary Resuscitation

    Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats. [Animal study shows hydrogen improves cardiac function after cardiac arrest.]

    2015

    Cardiac Dysfunction

    Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. [Animal study shows hydrogen improves heart function and reduces heart dysfunction caused by high glucose levels caused by diabetes.]

    2015

    Atherosclerosis

    Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. [Animal study shows hydrogen has an inhibitory effect and improves the stability of atherosclerotic plaque]

    2012

    Cardiac Arrest

    H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. [Animal study shows hydrogen reduces the mortality rate and increases the rate of resuscitation rate after cardiac arrest.]

    2014

    Cardiac Arrest

    Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management [Animal study shows hydrogen improves the outcome and resuscitation rate after cardiac arrest.]

    2018

    Vascular Aging of Aorta

    Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice [Animal study shows hydrogen decreased the markers of vascular aging and cholesterol levels]

    HYDROGEN RESEARCH ON CANCER

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    The articles  in this section show that hydrogen water inhibits cancer progression and improves the prognosis of cancer patients.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2019

    Colorectal cancer

    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer [Human study shows hydrogen reverses imbalances caused by chemotherapy and improved prognosis of stage IV cancer patients.]

    2017

    Colorectal Cancer [LIVER]

    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy. [A controlled, randomized, single-blind human clinical study shows that hydrogen water alleviates liver injury due to chemotherapy.]

    2018

    Lung Cancer

    Hydrogen gas inhibits lung cancer progression through targeting SMC3. [Animal study shows hydrogen inhibits lung cancer progression.]

    2017

    Colon Cancer Inhibition

    Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. [Animal study shows hydrogen improves the survival rate of mice with colon cancer and has anticancer functions, particularly in combination with 5-fluorouracil.]

    2013

    Mitochondria's  huge Influence on Cancer

    Mitochondria and Cancer, Past, Present and Future  [A summary of the research on mitochondria's influence on cancer.

    2009

    Alleviates Cancer Drug Side-Effects

    Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice [Animal study shows hydrogen helps protect against cisplatin-induced toxicity showing it has potential for improving the quality of life of patients undergoing chemotherapy.]

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    The studies listed in this section show the effects of hydrogen on the heart.

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    These studies show that hydrogen water reduces inflammation, assists immune responsiveness and has a protective effect on the lungs.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2017

    anti-inflammatory [RHINITIS]

    Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model [Animal study shows hydrogen reduces allergic inflammation.]

    2017

    anti-inflammatory [Lung Injury from O2 THERAPY]

    Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1 [Animal study shows that hydrogen has a protective effect against oxygen induced lung injury and reduces edema.]

    2015

    anti-inflammatory [EXERCISE]

    Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise [Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]

    2009

    Immune System

    The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. [Animal study shows hydrogen water assists immune responsiveness.]

    HYDROGEN RESEARCH ON STROKE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    hese studies show that hydrogen water protects against oxidative damage in many ways. It protects the brain, nerves & arteries, improves recovery rate after a stroke, and protects against a stroke. 

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2017

    Cerebral infarction (acute)

    Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection [A randomized controlled human clinical study of patients with acute cerebral infarctions showed no harmful effects and better recovery rates.]

    2017

    Neuroblastoma

    Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis. [A human cultured neuroblastoma, pre-treated with hydrogen, was protected against H2O2 induced cell death.]

    2019

    Glioblastoma

    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation. [Animal study shows reduction in common brain tumors by inhaling hydrogen.]

    2018

    Traumatic Brain Injury

    Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. [Animal study shows hydrogen-rich water has a neuroprotective effect on the brain.]

    2018

    Mitochondria

    Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal chord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

    2018

    After stroke

    Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. [Animal study showing the neuroprotective effect of hydrogen.]

    2018

    Stroke

    Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. [Animal study showing that hydrogen helps improve recovery after stroke.]

    2018

    Severe Brain Injury

    Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. [Animal study showing that hydrogen has a neuroprotective effect on the brain and helps prevent or reduce the effects of brain injury.]

    2016

    Brain injury

    Effect of hydrogen-rich water on the angiogenesis in lesion boundary brain tissue of traumatic brain [Animal study shows hydrogen-rich water promotes angiogenesis and improves nerve function.]

    2015

    Neuroprotective

    Hydrogen has a neuroprotective effect via activation of Nrf-2/HO-1 pathway in ischemia reperfusion rat [Animal study shows that hydrogen has a neuroprotective effect against stroke.]

    2016

    Brain damage

    Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. [Animal study shows hydrogen reduces the effects of brain damage and prevents inflammation.]

    2016

    Brain infarction

    Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use. [Animal study shows hydrogen has a neuroprotective effect against cerebral damage.]

    2015

    Stroke

    Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats [Animal study shows hydrogen water can improve neurological function after a stroke.]

    2015

    Protects Against Stroke

    Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins. [Animal study shows hydrogen water helps to reduce brain infarct volume and improve neurological function following an induced brain injury.]

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    Hydrogen-water inhibits neuron loss, alleviates memory impairments, reduces size of brain tumors, and reduces the severity of multiple sclerosis.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2013

    Parkinson's

    Pilot study of H2 therapy in Parkinson's disease: A randomized double‐blind placebo‐controlled trial [A human controlled trial shows that drinking Hydrogen water was safe, and well tolerated. The patients who drank it showed significant improvement, while the control group who didn’t drink the hydrogen water worsened.]

    2019

    Vascular Dementia

    FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. [Animal study shows drinking hydrogen water inhibits neuron loss and alleviates memory impairments due to vascular dementia.]

    2019

    Glioblastoma

    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation. [Animal study shows reduction in common brain tumors by inhaling hydrogen.]

    2018

    Mitochondria

    Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal chord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

    2018

    Mild Cognitive Impairment

    Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. [Animal study showing that hydrogen water helps to suppress dementia and other oxidative stress.]

    2018

    Cognitive Impairment

    Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance. [Animal study showing that hydrogen significantly helps cognitive behavior and reduced oxidative stress and inflammation in the brain. This study noted that there was an even more profound effect in the female brains than male.]

    2015

    Multiple Sclerosis

    Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice. [Animal study shows hydrogen water helps to both delay the onset of and reduce the severity of induced multiple sclerosis.]

    2015

    Altzheimer's

    Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. [Animal study shows hydrogen water reduces reactive oxygen induced cell death and stimulates healing.]

    2014

    Age related Neurological Diseases

    Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage [Animal study shows hydrogen water protects cells from oxidative stresses.]

    HYDROGEN RESEARCH ON DIABETES

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    Our UV water purification systems use ultraviolet light to eliminate bacteria and viruses present in your water, providing you with safe and healthy drinking water.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2008

    Diabetes [GLUCOSE TOLERANCE]

    Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. [A randomized double-blind human study shows hydrogen helped decrease oxidative stress and insulin resistance and improved glucose metabolism.]

    2013

    Diabetes [GLUCOSE UPTAKE]

    Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle [Animal study shows hydrogen improves glucose control.]

    2011

    Diabetes [Pt NANOPARTICLES]

    Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles [Animal study shows both hydrogen water and the nano platinum in ionized water improve glucose signaling pathways.]

    2006

    Diabetes [ANTI-DIABETIC EFFECTS]

    Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. [Animal study shows hydrogen improves blood glucose control.]

    2006

    Diabetes [BETA CELL PROTECTION]

    Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. [Animal study shows hydrogen improves blood glucose tolerance, increases blood insulin and reduces blood glucose.]

    2005

    Diabetes [BETA CELL PROTECTION]

    Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species. [Animal study shows hydrogen enhances glucose-sensitivity, glucose response of beta-cells and protects pancreatic beta-cells from alloxan-induced cell damage.]

    Benefits Demonstrated in Research Studies & Clinical Trials

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    Spanning over 20 years worth of treating patients with ionized water Blood Pressure  

    Use of Ionized water in hypochlorhydria or achlorhydria Prof. Kuninaka Hironage, Head of Kuninaka Hospital

    "The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels ."

    2017

    Myocardial Infarction

    The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans. [Human study shows inhaling hydrogen is safe and improves the markers of hypertension.]

    2019

    Hypertension

    Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. [Animal study shows hydrogen reduces hypertension and left ventricular hypertrophy.]

    2018

    Chronic Heart Failure

    Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. [Animal study shows hydrogen reduces the symptoms of chronic heart failure.]

    2016

    Cardiopulmonary Resuscitation

    Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats. [Animal study shows hydrogen improves cardiac function after cardiac arrest.]

    2015

    Cardiac Dysfunction

    Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. [Animal study shows hydrogen improves heart function and reduces heart dysfunction caused by high glucose levels caused by diabetes.]

    2015

    Atherosclerosis

    Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. [Animal study shows hydrogen has an inhibitory effect and improves the stability of atherosclerotic plaque]

    2012

    Cardiac Arrest

    H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. [Animal study shows hydrogen reduces the mortality rate and increases the rate of resuscitation rate after cardiac arrest.]

    2014

    Cardiac Arrest

    Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management [Animal study shows hydrogen improves the outcome and resuscitation rate after cardiac arrest.]

    2018

    Vascular Aging of Aorta

    Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice [Animal study shows hydrogen decreased the markers of vascular aging and cholesterol levels]

    HYDROGEN RESEARCH ON CANCER

    The studies listed in this section show the effects of hydrogen on the heart.

    The studies listed in this section show the effects of hydrogen on the heart.

    The articles  in this section show that hydrogen water inhibits cancer progression and improves the prognosis of cancer patients.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2019

    Colorectal cancer

    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer [Human study shows hydrogen reverses imbalances caused by chemotherapy and improved prognosis of stage IV cancer patients.]

    2017

    Colorectal Cancer [LIVER]

    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy. [A controlled, randomized, single-blind human clinical study shows that hydrogen water alleviates liver injury due to chemotherapy.]

    2018

    Lung Cancer

    Hydrogen gas inhibits lung cancer progression through targeting SMC3. [Animal study shows hydrogen inhibits lung cancer progression.]

    2017

    Colon Cancer Inhibition

    Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. [Animal study shows hydrogen improves the survival rate of mice with colon cancer and has anticancer functions, particularly in combination with 5-fluorouracil.]

    2013

    Mitochondria's  huge Influence on Cancer

    Mitochondria and Cancer, Past, Present and Future  [A summary of the research on mitochondria's influence on cancer.

    2009

    Alleviates Cancer Drug Side-Effects

    Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice [Animal study shows hydrogen helps protect against cisplatin-induced toxicity showing it has potential for improving the quality of life of patients undergoing chemotherapy.]

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    The studies listed in this section show the effects of hydrogen on the heart.

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    These studies show that hydrogen water reduces inflammation, assists immune responsiveness and has a protective effect on the lungs.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2017

    anti-inflammatory [RHINITIS]

    Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model [Animal study shows hydrogen reduces allergic inflammation.]

    2017

    anti-inflammatory [Lung Injury from O2 THERAPY]

    Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1 [Animal study shows that hydrogen has a protective effect against oxygen induced lung injury and reduces edema.]

    2015

    anti-inflammatory [EXERCISE]

    Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise [Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]

    2009

    Immune System

    The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. [Animal study shows hydrogen water assists immune responsiveness.]

    HYDROGEN RESEARCH ON STROKE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON CHRONIC LOWER RESPIRATORY DISEASE

    hese studies show that hydrogen water protects against oxidative damage in many ways. It protects the brain, nerves & arteries, improves recovery rate after a stroke, and protects against a stroke. 

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2017

    Cerebral infarction (acute)

    Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection [A randomized controlled human clinical study of patients with acute cerebral infarctions showed no harmful effects and better recovery rates.]

    2017

    Neuroblastoma

    Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis. [A human cultured neuroblastoma, pre-treated with hydrogen, was protected against H2O2 induced cell death.]

    2019

    Glioblastoma

    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation. [Animal study shows reduction in common brain tumors by inhaling hydrogen.]

    2018

    Traumatic Brain Injury

    Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. [Animal study shows hydrogen-rich water has a neuroprotective effect on the brain.]

    2018

    Mitochondria

    Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal chord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

    2018

    After stroke

    Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. [Animal study showing the neuroprotective effect of hydrogen.]

    2018

    Stroke

    Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. [Animal study showing that hydrogen helps improve recovery after stroke.]

    2018

    Severe Brain Injury

    Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. [Animal study showing that hydrogen has a neuroprotective effect on the brain and helps prevent or reduce the effects of brain injury.]

    2016

    Brain injury

    Effect of hydrogen-rich water on the angiogenesis in lesion boundary brain tissue of traumatic brain [Animal study shows hydrogen-rich water promotes angiogenesis and improves nerve function.]

    2015

    Neuroprotective

    Hydrogen has a neuroprotective effect via activation of Nrf-2/HO-1 pathway in ischemia reperfusion rat [Animal study shows that hydrogen has a neuroprotective effect against stroke.]

    2016

    Brain damage

    Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. [Animal study shows hydrogen reduces the effects of brain damage and prevents inflammation.]

    2016

    Brain infarction

    Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use. [Animal study shows hydrogen has a neuroprotective effect against cerebral damage.]

    2015

    Stroke

    Hydrogen improves neurological function through attenuation of blood–brain barrier disruption in spontaneously hypertensive stroke-prone rats [Animal study shows hydrogen water can improve neurological function after a stroke.]

    2015

    Protects Against Stroke

    Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins. [Animal study shows hydrogen water helps to reduce brain infarct volume and improve neurological function following an induced brain injury.]

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    Hydrogen-water inhibits neuron loss, alleviates memory impairments, reduces size of brain tumors, and reduces the severity of multiple sclerosis.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2013

    Parkinson's

    Pilot study of H2 therapy in Parkinson's disease: A randomized double‐blind placebo‐controlled trial [A human controlled trial shows that drinking Hydrogen water was safe, and well tolerated. The patients who drank it showed significant improvement, while the control group who didn’t drink the hydrogen water worsened.]

    2019

    Vascular Dementia

    FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. [Animal study shows drinking hydrogen water inhibits neuron loss and alleviates memory impairments due to vascular dementia.]

    2019

    Glioblastoma

    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation. [Animal study shows reduction in common brain tumors by inhaling hydrogen.]

    2018

    Mitochondria

    Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. [Animal study shows the neuroprotective effect of hydrogen on the neurons in the spinal chord. Hydrogen was also seen to help the neurons and their mitochondria to heal after damage.]

    2018

    Mild Cognitive Impairment

    Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. [Animal study showing that hydrogen water helps to suppress dementia and other oxidative stress.]

    2018

    Cognitive Impairment

    Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance. [Animal study showing that hydrogen significantly helps cognitive behavior and reduced oxidative stress and inflammation in the brain. This study noted that there was an even more profound effect in the female brains than male.]

    2015

    Multiple Sclerosis

    Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice. [Animal study shows hydrogen water helps to both delay the onset of and reduce the severity of induced multiple sclerosis.]

    2015

    Altzheimer's

    Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. [Animal study shows hydrogen water reduces reactive oxygen induced cell death and stimulates healing.]

    2014

    Age related Neurological Diseases

    Electrochemically Reduced Water Protects Neural Cells from Oxidative Damage [Animal study shows hydrogen water protects cells from oxidative stresses.]

    HYDROGEN RESEARCH ON DIABETES

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    HYDROGEN RESEARCH ON ALTZHEIMER'S, MULTIPLE SCLEROSIS & PARKINSON'S DISEASE

    Our UV water purification systems use ultraviolet light to eliminate bacteria and viruses present in your water, providing you with safe and healthy drinking water.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2008

    Diabetes [GLUCOSE TOLERANCE]

    Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. [A randomized double-blind human study shows hydrogen helped decrease oxidative stress and insulin resistance and improved glucose metabolism.]

    2013

    Diabetes [GLUCOSE UPTAKE]

    Hydrogen Improves Glycemic Control in Type1 Diabetic Animal Model by Promoting Glucose Uptake into Skeletal Muscle [Animal study shows hydrogen improves glucose control.]

    2011

    Diabetes [Pt NANOPARTICLES]

    Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles [Animal study shows both hydrogen water and the nano platinum in ionized water improve glucose signaling pathways.]

    2006

    Diabetes [ANTI-DIABETIC EFFECTS]

    Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. [Animal study shows hydrogen improves blood glucose control.]

    2006

    Diabetes [BETA CELL PROTECTION]

    Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. [Animal study shows hydrogen improves blood glucose tolerance, increases blood insulin and reduces blood glucose.]

    2005

    Diabetes [BETA CELL PROTECTION]

    Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species. [Animal study shows hydrogen enhances glucose-sensitivity, glucose response of beta-cells and protects pancreatic beta-cells from alloxan-induced cell damage.]

    Benefits Demonstrated in Research Studies & Clinical Trials

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2013

    Cholesterol level Balancing

    Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome. [This is a human study which shows drinking ionized water helps cholesterol levels.]

    2018

    Liver & Cholesterol

    Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice [Animal study shows drinking ionized water helps intestinal fermentation.]

    HYDROGEN RESEARCH ON INTESTINES & STOMACH

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood


    Hydrogen rich water is healthy for gut flora. Helps improves symptoms of diarrhea and irritable bowels. It protects the intestines against the ill-effects of chemo-therapy or radiation.

    YEAR

    TOPIC/SUBJECT

    TITLE OF SCIENTIFIC ARTICLE

    2019

    Gut Flora

    Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China  [This is a human study which shows hydrogen-rich water was healthy for gut flora]

    2019

    Gastrointestinal Symptoms

    Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms  [This is a human study which shows alkaline ionized water is effective in relieving abdominal complaints. Subjects drinking ionized water also had better rest at night and woke in the morning with more energy.]

    2018

    Irritable Bowel Syndrome with Diarrhea

    Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study  [This is a human study which shows alkaline ionized water was helpful in improving the symptoms of diarrhea and irritable bowel syndrome.]

    2005

    Intestinal Health

    Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water. [This is a human study which shows that alkaline ionized water assists to properly balance the gut microflora. 

    2018

    Protects-Good Bacteria

    Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Fusarium Toxin-Contaminated Diet [Animal study shows that hydrogen-water has shown a protective effect on the balance of intestinal microbiota.] 

    2018

    Intestinal Environment

    Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice [Animal study shows alkaline ionized water has benefit to intestinal microbes]

    2018

    GI Toxicity

    Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota [Animal study shows that drinking hydrogen-rich water improved the prognosis of mice undergoing radiation and was protective of the intestines.]

    2017

    Inflammatory Bowel Disease

    Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression [Animal study shows shows hydrogen-rich water protects against inflammatory bowel disease.]

    1996

    Intestinal Health

    Physiological effects of alkaline ionized water: Effects on metabolites produced by intestinal fermentation [Animal study shows alkaline ionized water was healthy for the intestines.]

    HYDROGEN RESEARCH ON SKIN Hydrogen has helped alleviate psoriasis, skin ulcers, and atopic dermatiti

    HYDROGEN RESEARCH ON CHOLESTEROL Hydrogen protects against the build-up of cholesterol in the blood

    HYDROGEN RESEARCH ON SKIN Hydrogen has helped alleviate psoriasis, skin ulcers, and atopic dermatiti

    YEAR

    TOPIC/SUBJECT

    TITLE OF SCIENTIFIC ARTICLE

    2018

    Psoriasis

    Positive effects of hydrogen-water bathing in patients of psoriasis and parapsoriasis en plaques [This is a human study which shows hydrogen water bathing is beneficial to psoriasis.]

    2013

    Skin Ulcers

    Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro [This is a human study which shows intake of hydrogen water helps the reconstruction of normal skin cells.] 

    2012

    Skin Diseases

    Hydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers. [This is a human study which shows hydrogen helped with the prognosis of inflammation of the skin.] 

    2012

    Wrinkles

    Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes. [This is a human study which shows hydrogen water bathing helps to repress UVA-induced wrinkles.

    2013

    Dermatitis

    The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice. [Animal study shows hydrogen water has a positive effect on atopic dermatitis.]

    HYDROGEN RESEARCH ON ANTI-INFLAMMATORY

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    HYDROGEN RESEARCH ON SKIN Hydrogen has helped alleviate psoriasis, skin ulcers, and atopic dermatiti

    Hydrogen reduces inflammation and edema and assists with immune-responsiveness.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2014

    Sports-Related Soft Tissue Injuries

    Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. [Human study of professional athletes shows faster recovery times when injured for those who were given hydrogen supplements daily during the season.]

    2017

    anti-inflammatory [RHINITIS]

    Effect of hydrogen-rich saline on the CD4(+) CD25(+) Foxp3(+) Treg cells of allergic rhinitis guinea pigs model[Animal study shows hydrogen reduces allergic inflammation.]

    2017

    anti-inflammatory [PANCREATITIS]

    Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss. [Animal study shows hydrogen helped to prevent and reduce pancreatitis.]

    2017

    anti-inflammatory [Lung Injury from O2 THERAPY]

    Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1 [Animal study shows that hydrogen has a protective effect against oxygen induced lung injury and reduces edema.]

    2016

    anti-inflammatory [PANCREATITIS]

    Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis [Animal study shows hydrogen has a protective effect against oxidative damage and reduces inflammation.]

    2016

    anti-inflammatory [ARTHRITIS]

    Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress [Animal study shows hydrogen slows down the progression of rheumatoid arthritis.]

    2015

    anti-inflammatory [EXERCISE]

    Hydrogen-rich water inhibits mitochondrial oxidative stress and inflammation in the skeletal muscle after eccentric exercise [Animal study shows [Animal study shows hydrogen reduces inflammation after exercise.]

    2001

    anti-inflammatory [LIVER]

    Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. [Animal study shows hydrogen has an anti-inflammatory effect.]

    2009

    Immune System

    The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.[Animal study shows hydrogen water assists immune responsiveness.]

    HYDROGEN RESEARCH ON ANTI-OXIDANT

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2012

    Platelets

    Hydrogen may inhibit collagen-induced platelet aggregation: an ex vivo and in vivo study [This is a human and animal study which shows hydrogen may inhibit collagen-induced platelet aggregation.]

    2016

    Antioxidant

    Effects of Hydrogenized Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signaling and SIRT 1 and elomerase Activity [in vitro study shows that commercial hydrogen water is effective in antioxidant properties.]

    2017

    Bone-Health

    Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. [Animal study shows hydrogen prevents steroid-induced osteonecrosis.]

    2011

    Eyes - Cornea

    Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.[Animal study shows hydrogen helps prevent blindness caused by alkali burn.]

    2017

    Obesity

    Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. [Animal study shows hydrogen-rich water suppressed body weight gain and reduced oxidative stress.]

    2011

    Obesity & Diabetes

    Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. [Animal study shows hydrogen stimulated energy metabolism, improving obesity, diabetes and metabolic syndrome.]

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    HYDROGEN RESEARCH ON ANTI-AGING Hydrogen improves cell function, cell longevity, and protects DNA.

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2018

    Reduction of Senescence-Associated Cells

    Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo [Animal study shows hydrogen is a protective anti-aging treatment.]

    2017

    Anti-Aging & Cell Death

    Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage [Animal study shows hydrogen protects against aging and cell death.]

    2016

    Longevity

    Alkaline Water and Longevity [3-year survival study shows alkaline ionized water improves strength and longevity of mice.]

    2010 

    Anti-Aging; Bones

    Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials. [In vitro study shows hydrogen prolongs the lifespan of cells.]

    2013

    Increased Lifespan

    Electrolyzed-reduced water increases resistance to oxidative stress, fertility, and lifespan via insulin/IGF-1-like signal in C. elegans. [Animal study shows hydrogen helps to resist oxidative stress and aging.] 

    1997

    Protects DNA

    Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. [Animal study shows hydrogen helps to protect DNA and scavenges harmful radicals.]

    HYDROGEN RESEARCH ON EYES

    HYDROGEN RESEARCH ON EYES

    HYDROGEN RESEARCH ON EYES

    YEAR

    TOPIC/SUBJECT

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

    2019

    Retinal Vein Occlusion

    Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression.  [Animal study shows hydrogen helps alleviate retinal edema and improve its function.] 

    2011

    Cornea

    Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. [Animal study shows hydrogen helps prevent blindness from alkali burn.]

    2010

    Retina

    Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Oharazawa H1, Igarashi T, Yokota T. [Animal study shows hydrogen loaded eye drops are highly useful and neuroprotective]

    OTHER Research

    HYDROGEN RESEARCH ON EYES

    HYDROGEN RESEARCH ON EYES

    YEAR

    TOPIC/SUBJECT

    LINK

    TITLE/DESCRIPTION OF SCIENTIFIC ARTICLE

     Spanning over 30 years Gynecology 

    Use of Ionized water for gynecological conditions Prof. Watanabe Ifao, Watanabe Hospital

    "Ionized alklaine antioxidant water improves body constituents and ensures effective healing to many illnesses. The uses of antioxidant water in gynecological patients have proved to be very effective. The main reason for its effectiveness is that this water can neutralize toxins.

    When given antioxidant water to pre-eclamptic toxemia cases, the results are most significant. During my long years of servicing the pre-eclamptic toxemia cases, I found that the women with pre-eclamptic toxemia who consumed antioxidant water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group showed intelligence above average."

    2011

    Radiotherapy

    PubMed

    Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. [A randomized placebo controlled human study shows therapeutic benefits for drinking hydrogen-rich water before, during and after radiation treatments]

    2011

    Weight Loss

    HighBeam

    The effect of daily consumption of 2 liters of electrolyzed water for 2 months on body composition and several physiological parameters in four obese subjects: a preliminary report.  [This was a human trial to see if alkaline ionized water would influence the ability of four obese patients to lose weight. The average weight loss reported during the two-month trial was 12 pounds. No other variable was introduced. No toxins were in the water, yet increased toxins were in the urine test, which indicates the body was able to detox several of the tested heavy metals.]

    2016

    Blood Viscosity

    BioMed Central

    Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults[Human study shows high pH water drunk after exercise to be more hydrating. The blood viscosity was tested, and shown to be better, in the group who drank alkaline ionized water vs. acceptable standard purified water.]

    2018

    Pregnancy: Protective Benefits Spread to Newborn

    PubMed

    Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. [Animal study shows that giving H2 to the mother is protective for the newborn]

    2017

    Hemorrhagic Shock

    PubMed

    Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats.[Animal study shows treatment with H2 inhalation stabilizes the blood pressure until curative treatment can be performed.]

    2014

    Hearing Loss (noise-induced)

    PubMed

    Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species. [Animal study shows H2 inhalation is protective against noise induced hearing loss.] 

    2016

    Sepsis

    PubMed

    Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.[Animal study shows molecular hydrogen improves chances of survival]

    2016

    Motor Deficits

    Tandfon-line

    Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice [Animal study shows hydrogen improves prognosis for muscular dystrophy] 

    2016

    Bladder

    PubMed

    Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction.[Animal study shows H2 is protective against bladder dysfunction.]

    2009

    Hearing: Auditory Hair Cells

    PubMed

    Hydrogen protects auditory hair cells from free radicals. [In vitro study shows hydrogen to be protective against cell death of auditory hair cells.]

    2014

    Prevention Medicine

    PubMed

    Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.

    2009

    Metabolic Acidosis

    PubMed

    Ionized alkaline water: new strategy for management of metabolic acidosis in experimental animals [Animal study shows alkaline ionized water can manage metabolic acidosis safely.]

    2009

    Hangovers

    PubMed

    Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats [Animal study shows drinking alkaline ionized water has a detox effect from ethanol]

    2017

    ERW Superior to other H2Water

    PubMed

    Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. [In vitro study shows that alkaline ionized water has additional antioxidative factor, likely to be platinum nanoparticles, which makes it superior to other hydrogen applications for scavenging radicals.]

    Video

    IONIZED WATER USED TO CURE DIABETIC NECROSIS

    50 YEARS OF RESEARCH SHOWING THE HEALING POWER OF IONIZED WATER

    The Japanese use of water ionizers in their research is an interesting story. Japanese have the longest life spans and lowest infant mortality rate in the world. Why?

    Watch the video and read this article:

    How Exactly Do What Ionizers Work?

    What Water Ionizers Do:

    Water ionizers work by by using electromagnetism to change ordinary tap water into ionized alkaline water with acid-fighting alkalinity and antioxidant potential. Plain water is a mix of alkaline minerals and carbonate – dissolved CO2. A water ionizer separates the carbonate from tap water from the alkaline minerals. The alkaline minerals, and the acidic carbonate are discharged in a separate streams of water. By separating the alkaline elements in tap water from the acidic elements, a water ionizer enables you to get the benefit of the natural acid-fighting alkalinity the alkaline minerals in your water like calcium and magnesium. These alkaline minerals, once freed of the carbonate, gain antioxidant potential and acid fighting alkalinity.

    How Water Ionizers work – The Process of Electrodialysis

    Inside a water ionizer, water runs across charged plates which are separated by a special membrane – called an Ion-Permeable Membrane. That membrane allows energetically charged atoms and molecules – called ions – to pass through. It doesn’t allow energetically neutral atoms and molecules to pass through. Water molecules are energetically neutral, so they don’t pass through the membrane. The alkaline mineral ions in water, and the carbonate ions in water both have energetic charges, so they’re allowed to pass through. This separates the alkaline minerals from the acidic carbonate.

    The alkaline minerals in water have a positive energetic charge – that makes them positively charged ions.

    Likewise, the acidic carbonate in water have a negative electrical charge, which makes them negatively charged ions.

    The electromagnetically charged plates in a water ionizer separate those ions. The positively charged alkaline mineral ions are attracted to the negative plates. The acidic carbonate is attracted to the positively charged plates. The ion-permeable membrane allows both the positively charged alkaline mineral ions, and the negatively charged carbonate ions to pass through it, which then separates these ions into two chambers.


    Water ionizers make two streams of water

    Once separated, the ions in both chambers react with the water that’s inside each chamber to make alkaline and acidic waters. Each type of water is discharged a separate stream coming out of the water ionizer. The alkaline minerals are discharged in the alkaline stream as alkaline mineral water. The acidic carbonate is discharged in the acidic water stream as a solution of carbonic acid. When you dissolve CO2 into water, it makes carbonic acid.


    Why Alkaline water has Age-Fighting Antioxidant Potential

    Once freed of the acidic carbonate, the calcium and magnesium ions in the water are highly unstable. They immediately react with water molecules by grabbing a hydroxyl ion from them to form alkaline mineral hydrates. The alkaline minerals’ positive energetic charge is able to take a hydroxyl ion from a water molecule because it overcomes the energetic force holding the water molecule together. When this happens, the alkaline mineral ion gains the hydroxyl ion, and an atom of hydrogen is released. It is because of this reaction that alkaline water from a water ionizer is rich in hydrogen.

    Thanks to the negative energetic charge of the hydroxyl ion, the alkaline water in a water ionizer gains a negative energetic charge, which is called Oxidation Reduction Potential (ORP). The negative ORP of alkaline water from a water ionizer gives it the ability to reduce oxidative substances, such as free radicals and reactive oxygen species. Oxidative substances in the body are believed to be a major factor in disease and aging. It is the Oxidation Reduction Potential of alkaline water that gives it the potential to work as an antioxidant.

    Why Alkaline Water is Different from Tap Water

    Alkaline water from a water ionizer is different from tap water because the mineral hydrates in alkaline water give it healthy qualities that you don’t get from tap water:

    • Acid fighting alkalinity – Alkaline water can neutralize acids
    • Antioxidant potential – Alkaline water reduces harmful oxidation
    • Better taste – Alkaline water is slightly sweeter and a lot more refreshing!

    Tap water doesn’t have any of those healthy qualities because those healthy benefits are locked up by the acidic carbonate in tap water. The acidic carbonate simply balances out the alkaline minerals, making tap water energetically neutral. Perhaps that’s the reason why tap water tastes ‘dead’ compared to alkaline water!

    What is ionized water?

    • Ionized water is water with mineral ions in it. Minerals in water become ionized when they either gain or lose electrons. All water found in nature has minerals in it.
    • Ionized water has minerals in it. All water found in nature is ionized to some extent.
    • Deionized water has no minerals in it. It is made by distilling water or through reverse osmosis.
    • Water with no minerals in it is not natural water, all natural water has minerals in it.

    Two Kinds of Ionized Water

    Ionized alkaline water is also known as Electrolyzed Reduced Water because it has been shown in laboratory settings to reduce the effects of oxidation. The ability of ionized alkaline water to reduce oxidative damage is referred to as its Oxidation Reduction Potential (ORP).

    Oxidation – Happens when an acidic substance steals electrons from a substance. Oxidation will damage or destroy a substance; it causes cut apples to turn brown, and metal to rust. Acidic water oxidizes things – including body tissues and DNA, by stealing electrons from them. Doctors recommend antioxidant foods to stop the damage caused by oxidation.

    Reduction – Happens when an antioxidant substance gives electrons to a substance such as free radicals that attack body tissues and DNA. The antioxidant reduces the free radicals ability to oxidize tissues and DNA. Medical science suggests this process help keep you healthy.

    Ionized alkaline water is known by scientists as Electrolyzed Reduced Water, because it reduces oxidation. ERW has extra electrons which can reduce the ability of harmful substances to oxidize things like tissues and DNA. Research into the health benefits of the reduction caused by ERW is ongoing.

    Ionized acidic water is known by scientists as Electrolyzed Oxidative Water (EOW) because it increases oxidation. It’s ability to increase oxidation gives EOW the ability to sanitize surfaces, tools, kitchen implements and more. When it’s made with salt, EOW becomes a powerful acidic water that replaces many toxic household cleaners.

    How is Ionized Water Made?

    Tap water is a mixture of two kinds of ions: Mineral ions, such as calcium, magnesium and potassium, and bicarbonate ions. Those mineral ions have a positive electromagnetic charge. Bicarbonate is dissolved CO2, it’s formed when CO2 is absorbed by water from the air. Bicarbonate has a negative electromagnetic charge.

    Home water ionizers use electromagnetism to separate the positively charged minerals from the negatively charged bicarbonate. Water ionizers have charged plates, which act just like magnets, they attract the ions that have the opposite charge they do. When that happens, the ions pass through a membrane called a Bipolar Exchange Membrane. The membrane allows ions to pass through it, but it doesn’t allow other types of particles to cross.

    The ion separation process makes both alkaline and acidic waters at the same time because the membrane separates the minerals from the bicarbonate. That makes the water inside the alkaline chamber into alkaline water, and the water inside the acidic chamber into acidic water.

    In-Vitro Study on ionized water shows it can reduce oxidative damage to DNA strands.

    The study, called Electrolyzed–Reduced Water Scavenges Active Oxygen Species and Protects DNA from Oxidative Damage examined ionized alkaline water’s ability to stop oxidative damage done to our DNA by harmful oxidants like free radicals. Oxidation by free radicals has been linked to premature aging and degenerative disease.

    Electrolyzed–Reduced Water Scavenges Active Oxygen Species and Protects DNA from Oxidative Damage☆

    Author links open overlay panelSanetaka Shirahata a 1, Shigeru Kabayama a, Mariko Nakano a, Takumi Miura a, Kenichi Kusumoto a, Miho Gotoh a, Hidemitsu Hayashi b, Kazumichi Otsubo c, Shinkatsu Morisawa c, Yoshinori Katakura a

    Abstract

    Active oxygen species or free radicals are considered to cause extensive oxidative damage to biological macromolecules, which brings about a variety of diseases as well as aging. The ideal scavenger for active oxygen should be ‘active hydrogen’. ‘Active hydrogen’ can be produced in reduced water near the cathode during electrolysis of water. Reduced water exhibits high pH, low dissolved oxygen (DO), extremely high dissolved molecular hydrogen (DH), and extremely negative redox potential (RP) values. Strongly electrolyzed–reduced water, as well as ascorbic acid, (+)-catechin and tannic acid, completely scavenged O•−2produced by the hypoxanthine-xanthine oxidase (HX-XOD) system in sodium phosphate buffer (pH 7.0). The superoxide dismutase (SOD)-like activity of reduced water is stable at 4°C for over a month and was not lost even after neutralization, repeated freezing and melting, deflation with sonication, vigorous mixing, boiling, repeated filtration, or closed autoclaving, but was lost by opened autoclaving or by closed autoclaving in the presence of tungsten trioxide which efficiently adsorbs active atomic hydrogen. Water bubbled with hydrogen gas exhibited low DO, extremely high DH and extremely low RP values, as does reduced water, but it has no SOD-like activity. These results suggest that the SOD-like activity of reduced water is not due to the dissolved molecular hydrogen but due to the dissolved atomic hydrogen (active hydrogen). Although SOD accumulated H2O2when added to the HX-XOD system, reduced water decreased the amount of H2O2produced by XOD. Reduced water, as well as catalase and ascorbic acid, could directly scavenge H2O2. Reduced water suppresses single-strand breakage of DNA by active oxygen species produced by the Cu(II)-catalyzed oxidation of ascorbic acid in a dose-dependent manner, suggesting that reduced water can scavenge not only O•−2and H2O2, but also1O2and•OH.

    Get More with Each Sip of Alkaline Water

    Fitting more antioxidants into your diet is one of the best things you can do for your body. Antioxidants help your body recover from disease and heavy exercise, and they have the physical benefit of slowing down your skin’s aging process. Antioxidants improve your inner and outer health, and they come in a variety of delicious foods and alkaline water.

    Benefits of ionized water

    The Purest and Freshest Alkaline Water

    Imagine having the ability too neutralize free radicals and give you the benefits mentioned above. Alkaline ionized water, or Hydra Water™ has a negative charge called oxidation reduction potential (-ORP). The ORP properties of alkaline water are known by many as simply “antioxidants”.

    To explain further, normal body functions cause high or rising oxidation in the body, which is not good. To fight against the oxidation, alkaline water’s negative ORP charge literally hinders the oxidation process by counteracting any rising oxidation effect. Ionized water essentially rejuvenates us. A glass of alkaline water brings us as close as we can ever hope to get to a Fountain of Youth, as incredible as that may sound.

    Is having gallons of alkaline water flowing freely just a dream?

    Not any more!

    The Symptoms of Dehydration Can Affect Your Brain Function

    Our brains are composed of around 73% water. If our brains become dehydrated, the effects can be profound on how we function.


    The symptoms of dehydration in the brain include:


    Reduction in cognitive skills

    Diminished memory capacity

    Impaired motor skills

    Negative impact on mood

    Confusion

    Fatigue

    Headaches

    Shrinking Brain – Scary!


    Physical changes in the brain due to dehydration are very noticeable.


    For example, headaches occur because the brain physically shrinks away from the skull, causing pain. This pain is relieved when your brain is hydrated again.


    There’s no room for doubt! Drinking enough water is critical for efficient brain function and mental focus…just make sure it’s hydrogen-rich alkaline water from one of our water ionizers!


    Why Hydra Alkaline Water is Best!


    When you start to think about how such a vital, complex, irreplaceable part of the human body is so dependent on water to function properly, it really gets you thinking about the quality of the water that you drink.



    Did you know? The average 150lbs. adult body contains almost 12 gallons of water. Almost 80% of our body is 'water weight' . 



    • Benefits of Hydrogen
    • What is Hydrogen Water
    • 8 Types Of Water
    • Lose weight with Hydra
    • Blog

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